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We examine how moment-to-moment fluctuations in arousal and attention affect brain and cognition. There are 3 main themes:

• The role of the locus coeruleus-norepinephrine system in human cognition
• The effects of phasic and tonic arousal on information processing
• Moment-to-moment fluctuations in attention and cognitive control

We investigate these topics using behavioral methods, EEG, fMRI, pharmacology, pupillometry, patients studies and computational modeling.